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Neonatal Pertussis, an Under-Recognized Health Burden and Rationale for Maternal Immunization: A Systematic Review of South and South-East Asian Countries

posted on 2019-04-30, 14:31 authored by Ashish Agrawal, Sanjeev Singh, Shafi Kolhapure, Walid Kandeil, Rishma Pai, Tanu Singhal

Full copyright for enhanced digital features is owned by GlaxoSmithKline Biologicals SA.

As well as a summary slide, this page also contains the following digital features:

Feature 1 Plain Language Summary - Focus on the Patient

Feature 1 highlights the context of the article, the importance of neonatal pertussis, maternal immunization and steps that should be taken in the future to address the impact of neonatal pertussis disease burden.

Feature 2 Transfer of Maternal Antibodies and Window of Vulnerability in Infants

Panel 1 demonstrates the physiological changes during the pregnancy period in unvaccinated mothers which would leave the newborn vulnerable to disease.

Panel 2 shows that vaccinated mothers confer protection to the newborn through the mechanism of maternal–fetal-antibody transfer.

Source: Adapted from Jones C, Heath P. Antenatal immunization. Hum Vaccin Immunother. 2014;10:2118-22.

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